Vesalius served successively as a physician for Emperor Chalres V and then later on his son Philip II of Spain. By beginning his anatomical work by the publication of six very detailed plates in his Tabulae Sex in 1538. Vesalius was most commonly known for his comprehensive and lavishing work illustrated of all Renaissance anatomical text, De humani corpris fabric libri septem, which is based on the structure of the human body. It appeared in many number of editions in several countries within a few years of it's initial publication at Basle. Vesalius was among the first to ever perform thorough cadaver dissections himself. With success also comes discriminations from people. Since Vesalius overthrew many of the hitherto-uncontested doctrines of the second century anatomist Galen and also he got a lot of criticism from other anatomists.